Does marijuana affect men and women differently? Many cannabis users probably haven’t stopped to ponder how their sex affects their body’s response to marijuana. But findings now suggest males and females do experience cannabis somewhat differently.
Findings published in the journal of “Drug and Alcohol Dependence” show that females build up tolerance to THC (marijuana’s psychoactive component) more quickly than males do.
Rebecca Craft, psychology professor at Washington State University, studied the effects of THC on male and female rats, and found that female rats “are at least 30 percent more sensitive than males to the pain-relieving qualities of THC.”