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Tasmanian devils evolve to resist deadly cancer

Andrew Storfer
Andrew Storfer

Tasmanian devils are evolving in response to a highly lethal and contagious form of cancer, a Washington State University researcher has found.

Andrew Storfer, WSU professor of biology, and an international team of scientists discovered that two regions in the genomes of Australia’s iconic marsupials are changing in response to the rapid spread of devil facial tumor disease (DFTD), a nearly 100 percent fatal and transmissible cancer first detected in 1996.

The work, published today in Nature Communications, suggests some Tasmanian devil populations are evolving genetic resistance to DFTD that could help the species avoid extinction.

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Licensing deal will help combat deadly cattle disease

A gene-editing technology developed at Washington State University is being licensed to Genus plc, a global animal genetics company, to develop cattle that are more resistant to bovine respiratory disease (BRD).

The outcome of a discovery by WSU researcher Subramaniam Srikumaran, the new technology and its translation to disease-resistant animals is an example of the WSU expertise behind the recently launched Functional Genomics Initiative (FGI). FGI was developed by the College of Veterinary Medicine in partnership with the College of Arts and Sciences and the College of Agricultural, Human and Natural Resource Sciences to address grand challenges around health and global food supply.

The goal of this initiative is to use gene-editing approaches and advanced reproductive technologies to produce livestock that will increase food production, enhance disease resistance and allow livestock to thrive as global demand for food increases. Funding for the initiative and a center dedicated to this work will lead to additional important discoveries.

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