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College of Arts and Sciences PLOS ONE

Researchers see popular herbicide affecting health across generations

Supp. Fig. 1 partial, map of US usageFirst, the good news. Washington State University researchers have found that a rat exposed to a popular herbicide while in the womb developed no diseases and showed no apparent health effects aside from lower weight.

Now, the weird news. The grand-offspring of that rat did have more disease, as did a great-grand offspring third generation.

“The third generation had multiple diseases and much more frequently than the third generation of unexposed rats,” said Michael Skinner, a Washington State University professor of biological sciences. At work, says Skinner, are epigenetic inheritance changes that turn genes on and off, often because of environmental influences. » More …